Ex parte CHARLTON et al. - Page 2




          Appeal No. 1996-0783                                       Page 2           
          Application No. 08/102,297                                                  

          derived from a reading of exemplary claims 1, 16 and 19, which              
          are reproduced below.                                                       
               1. A device for rapidly detecting an analyte in a volume               
          of biological fluid, wherein the volume is as low as five to                
          ten microliters, said device comprising:                                    
                    a) means for detecting said analyte; and                          
                    b) a separation matrix vertically adjacent,                       
          compressed     to and coincident with said detection means such             
          that           analyte applied to said separation means can                 
          move from said      separation matrix to said detection means,              
          wherein said separation matrix and said detection means are                 
          under a volume compression of between 14 to 43 percent;                     
                    c) a cover portion having an aperture, the cross-                 
                    sectional area of which aperture is less than 90                  
          percent of     the cross-sectional area of said separation                  
          matrix; and                                                                 
                    d) a base portion containing an access means to                   
          allow     detection of an analytical signal generated by the                
          detection      means.                                                       
          16. A process of rapidly detecting glucose in a volume of a                 
          biological fluid, wherein said volume is as low as five to 10               
          microliters, said process comprising the steps of:                          
                    a) a base portion having a transparent window;                    
                    b) a means for detecting glucose vertically adjacent              
          to said base portion and at least partially coincident with                 
               said window;                                                           
                    c) a separation matrix vertically adjacent to,                    
               compressed to and substantially coincident with said                   
                    detection means, wherein the detection means and the              










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