Appeal 1995-2560
Application 07/833,973
polymer
and polymeric like material of naturally occurring and
synthetic origin which include commercially available
celluloses such as sodium carboxymethylcellulose (see
column 14, lines 14 and 15). Zaffaroni further discloses
methods whereby the covalent attachment of the flavor
imparting agent to the polymer can be carried out. One
method involve[s (sic)] forming covalent bonds by
reacting
a pendant carboxyl group of a flavor imparting molecule
with a hydroxyl, amine, mercaptan group or the like on
the other reactant, wherein activation of a carboxyl
group
can be effected by the reaction of a carboxyl group with
various carbodiimides, carbodiimidazoles, Woodward’s
reagent
and the like to form highly active intermediates capable
of reacting with other groups in the presence of a
solvent
and under mild reaction conditions to yield the desired
compounds (see column 16, lines 30-60). This method
disclosed by Zaffaroni appears to be within the scope
of the method claimed by the Appellants when the instant
claimed polyanionic polysaccharide is
carboxymethylcellulose
and the activating agent is a carbodiimide. . . .
The Zaffaroni Patent further discloses other
ingredients that can be added to the nonnutritive flavor
imparting compound which include the yolk of eggs, milk
products, glutamic acid, glycine and alanine which are
within the scope of the instant claimed nucleophiles
disclosed in Claims 30 and 82 of the instant application
which sets forth the nucleophile being selected from a
group consisting of an amino acid amide, a monofunctional
amine, an amino acid ester, an amino alcohol, and amino
thiol, and amino phenol, an amino catechol, an amino
acid,
a salt of an amino acid, a peptide, and a protein.
Also see column 25, lines 55-60, which discloses the
flavor imparting compounds being combine[d, sic] with
medicinals and pharmaceutical formulations including
- 4 -
Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 13 Next
Last modified: November 3, 2007