Ex parte TAMURA - Page 4




               Appeal No. 1996-0111                                                                                                    
               Application 08/041,428                                                                                                  


                                                            Discussion                                                                 

                                             The rejections  under 35 U.S.C. § 103                                                     
                       In considering the issues raised by this appeal, we have considered the Examiner's                              
               Answer, the Supplemental Answer, the references relied on by the examiner, Appellant's                                  
               Brief and Reply Brief, the declarations of Dr. Brown and Dr. Coffey, as well as the record                              
               as a whole.                                                                                                             
               Claims 1-26:                                                                                                            

                       The examiner has cited references establishing a correlation between increased                                  
               levels of " -acid glycoprotein in the body fluids of humans (Fudenberg, Toyama, and                                     
                            1                                                                                                          
               Shell), rats (Ruhenstroth-Bauer) and dogs (Belpaire) and the presence in the animals of                                 
               certain disease or inflammatory conditions as compared to healthy animals. (Answer,                                     
               pages 5-6).  While acknowledging that none of the references disclose "using these                                      
               correlations as a basis for managing farm animals or experimental animals" (Answer,                                     
               page 6), the examiner concludes that (Answer, pages 6-7):                                                               
                       it would have been obvious to one of ordinary skill to use the widely available                                 
                       knowledge that increased " -AGP levels are indicative of disease or                                             
                                                        1                                                                              
                       inflammation to assess the health status of groups of animals and to take                                       
                       whatever action is necessary in order to diagnose the suspected condition                                       
                       and subsequently to treat the condition in order to save the diseased animal                                    
                       or to separate the affected animals from the healthy ones in order to prevent                                   
                       contagion.                                                                                                      




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