Appeal No. 1996-1080 Application No. 07/869,111 comparison of the alkyl and alkenyl substituents at the 9- oxime position of the erythromycin derivatives. Declarant has not stated that the results of the deoximation experiments are unexpected. In re Geisler, supra. For the foregoing reasons, we determine that the preponderance of evidence, based on the totality of the record including evidence and arguments for and against patentability, weighs in favor of obviousness within the meaning of § 103. Accordingly, the rejection of claims 1 and 2 under 35 U.S.C. § 103 over Faubl in combination with Watanabe and Kirk-Othmer is affirmed. D. Summary The rejection of claim 3 under 35 U.S.C. § 103 as unpatentable over Watanabe in combination with Faubl and Kirk- Othmer is affirmed. The rejection of claims 1 and 2 under 35 U.S.C. § 103 as unpatentable over Faubl in combination with Watanabe and Kirk-Othmer is affirmed. 13Page: Previous 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 NextLast modified: November 3, 2007