Ex parte CHEN - Page 8




          Appeal No. 1996-3017                                                         
          Application No. 08/851,810                                                   


          presented no objective evidence that adjusting the reaction                  
          mixture to an alkaline pH produces an unexpected result.                     
               We now turn to the examiner's rejection of claims 6-10,                 
          13, 19 and 20 under 35 U.S.C. § 103.  Independent claim 6                    
          calls for preparing alkyl-pyrazines by "heating, refluxing and               
          subliming" an aqueous medium containing ammonium ions and an                 
          acyloin compound as reactants.  While the primary references                 
          do not disclose sublimation, appellant does not dispute the                  
          examiner's factual determination that Evans discloses the                    
          isolation of alkyl-pyrazines by a sublimation technique.                     
          Since Weissberger evidences that sublimation was a well-known                
          technique for isolating volatile compounds, in general, and                  
          Evans evidences that it was known in the art to employ                       
          sublimation to isolate alkyl-pyrazines, we find no error in                  
          the examiner's conclusion that it would have been obvious for                
          one of ordinary skill in the art to employ such a well-known                 
          separation technique to isolate the alkyl-pyrazines produced                 
          by the methods of the primary references.  In effect, our                    
          analysis is much the same as that discussed above with respect               
          to the rejection of claim 2.                                                 



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