Appeal No. 1996-3330 Application 07/861,458 suggestion, or motivation found in the prior art whereby a person of ordinary skill in the field of the invention would make the substitutions required. That knowledge can not come from the applicants' invention itself. Diversitech Corp. v. Century Steps, Inc., 850 F.2d 675, 678-79, 7 USPQ2d 1315, 1318 (Fed. Cir. 1988); In re Geiger, 815 F.2d 686, 688, 2 USPQ2d 1276, 1278 (Fed. Cir. 1987); Interconnect Planning Corp. v. Feil, 774 F.2d 1132, 1143, 227 USPQ 543, 551 (Fed. Cir. 1985). The extent to which such suggestion must be explicit in or may be fairly inferred from, the references, is decided on the facts of each case, in light of the prior art and its relationship to the invention. It is impermissible, however, simply to engage in a hindsight reconstruction of the claimed invention using applicants' disclosed invention as a template and selecting elements from references to fill the gaps. In re Gorman, 933 F.2d 983, 986-987, 18 USPQ2d 1885, 1888 (Fed. Cir. 1991). Here, the examiner has provided no facts or evidence which would have reasonably led one of ordinary skill in this art to the method of isolating unknown structural homologues of genes identified in a phylogenetically related animal in the manner claimed. Where, as here, the examiner fails to establish a prima facie case of obviousness, the rejection is improper and will be overturned. In re Fine, 837 F.2d 1071, 1074, 5 USPQ2d 1596, 1598 (Fed. Cir.1988). The rejection of claims 38-54, 58-60, 66-81, and 85-87 under 35 U.S.C. § 103 is reversed. Other Issues 9Page: Previous 1 2 3 4 5 6 7 8 9 10 11 NextLast modified: November 3, 2007