Ex parte BECK et al. - Page 7





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          taught the ratios of vectors containing DNA sequences encoding              
          TSH" and $ subunits which would result in the production of                 
          biologically active TSH” (Examiner’s Answer, pages 4 and 5).                
               As explained in In re Wands, 858 F.2d 731, 737, 8 USPQ2d               
          1400, 1404 (Fed. Cir. 1988):                                                
               Factors to be considered in determining whether a disclosure would require undue
               experimentation have been summarized by the board in Ex parte Forman, [230 USPQ
               546, 547 (BdPatAppInt 1986)].  They include (1) the quantity of experimentation
               necessary, (2) the amount of direction or guidance presented, (3) the presence or
               absence of working examples, (4) the nature of the invention, (5) the state of the
               prior art, (6) the relative skill of those in the art, (7) the predictability or
               unpredictability of the art, and (8) the breadth of the claims. (footnote omitted).
          Here, the fact finding needed to support the examiners                      
          assertion of undue experimentation has not been done.                       
               Accordingly, the rejection of claims 7, 13, 15 through                 
          22, 24, 28, 36, 81, 82, 89, 90, 92 and 93 under 35 U.S.C. §                 
          112, first paragraph is reversed.                                           
                                    OTHER ISSUES                                      
               We note the issuance of U.S. Patent 5,639,639 to                       
          appellants.  Patented claim 10 appears to be so similar to the              
          present claims as to raise the issue of obviousness-type                    


          double patenting.  It is suggested that the examiner and                    
          appellants review the patent upon return of the application to              



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