Appeal No. 1997-0204 Application No. 08/400,786 We have carefully reviewed the specification, claims and applied prior art, including all of the arguments advanced by both the examiner and appellants in support of their respective positions. This review leads us to conclude that the examiner’s § 103 rejections are not well founded. We reverse each of the examiner’s § 103 rejections for essentially those reasons set forth in the Brief. We add the following primarily for emphasis and completeness. The claimed subject matter is directed to a device for detecting an analyte in a biological fluid. The device includes “a separation matrix containing an agglutinating agent and between 70 and 150 millimolar of 4-(2-hydroxyethyl)- 1-piperazine-ethanesulfonic acid (HEPES)” and means for detecting the analyte. See claim 28. The presence of the HEPES buffer in the separation matrix is said to provide a faster endpoint detection. Id. The examiner states that both Chu ‘485 and ‘843 disclose essentially the device recited in claims 28, except that they fail to include between 70 and 150 millimolar of HEPES in their separation matrix. See Answer, pages 4, 5, 7, 8 and 9. The examiner then relies on Wilk to demonstrate that it would 4Page: Previous 1 2 3 4 5 6 7 8 9 NextLast modified: November 3, 2007