Appeal No. 1997-0204 Application No. 08/400,786 the separation matrix, prior to their use, so as not to impair the plasma separating properties of the separation matrix. See column 6, lines 8-18. Even if HEPES is not removed from the separation matrix described in Wilk as alleged by the examiner (Answer, page 13-14), Wilk's example 2 shows at best the inclusion only 10 millimolar of HEPES in the separation matrix (Wilk, column 8, lines 48-51). Thus, we agree with appellants that the applied prior art as whole would not have suggested including the claimed amount of HEPES (at least seven times more than that shown in Wilk) in the separation matrix of Chu’s assaying device. Accordingly, on this record, the examiner has not established a prima facie case of obviousness regarding the claimed subject matter within the meaning of 35 U.S.C. § 103. In view of the foregoing, the decision of the examiner is reversed. No time period for taking any subsequent action in connection with this appeal may be extended under 37 CFR § 1.136(a). REVERSED 6Page: Previous 1 2 3 4 5 6 7 8 9 NextLast modified: November 3, 2007