Appeal No. 1997-0875 Application No. 07/998,128 55. A tissue repair promoting composition comprising tissue repair promoting substances isolated from plasma and tissue repair promoting substances isolated from platelets, the tissue repair promoting substances isolated from plasma including at least fibrinogen, the composition being substantially free of fibrin. 68. The composition of Claim 55 wherein the tissue repair promoting substances are isolated from the plasma and platelets of a single human or animal. The references relied on by the examiner are: Schwarz et al. (Schwarz) 4,377,572 Mar. 22, 1983 Zimmerman et al. (Zimmerman) 4,453,939 Jun. 12, 1984 Sundsmo et al. (Sundsmo) 4,760,131 Jul. 26, 1988 Mann 2 146 335 Apr. 17, 1985 (UK Patent Application) Rose et al. (Rose) WO 86/01814 Mar. 27, 1986 (International Patent Application) Senior et al. (Senior), "Chemotactic Activity of Platelet Alpha Granule Proteins for Fibroblasts," The Journal of Cell Biology, Vol. 96, pp. 382-385 (February 1983) A reference relied on by appellant (brief, p. 7) is: Knighton 5,165,938 Nov. 24, 1992 ISSUE Claims 55-64, 67 and 68 stand rejected under 35 U.S.C. § 103 as being unpatentable over Schwarz, Sundsmo, Zimmerman, Mann, Senior and Rose. We reverse. - 2 -Page: Previous 1 2 3 4 5 6 7 8 9 10 NextLast modified: November 3, 2007