Appeal No. 1997-0875 Application No. 07/998,128 In reaching our decision in this appeal we have given careful consideration to the appellant's specification and claims and to the respective positions articulated by the appellant and the examiner. We make reference to the examiner's answer (Paper No. 24, mailed June 26, 1996) for the examiner's reasoning in support of the rejection and to the appellant's brief (Paper No. 17, filed May 8, 1995) and to the appellant's reply brief (Paper No. 25, filed August 26, 1996) for the appellant's arguments thereagainst. THE INVENTION According to appellant, The invention comprises a tissue repair promoting composition comprising tissue repair promoting substances isolated from plasma and tissue repair promoting substances isolated from platelets, the composition being substantially free of fibrin. The tissue repair promoting substances isolated from plasma include at least fibrinogen and may further include factor XIII and fibronectin. The tissue repair promoting substances isolated from platelets may include platelet-derived growth factor, epidermal growth factor, and platelet factors 1-4. The tissue repair promoting substances may be isolated from the plasma and platelets of a single human or animal. [Brief, pp. 1-2, citations to the specification omitted.] The claimed tissue repair promoting composition can be used as one component of a two- component tissue-adhesive system, the other component being, e.g., a solution of thrombin, calcium ions and aproprotin. The fibrinogen in the claimed composition is converted to fibrin by application of the second component, i.e., thrombin. (See specification, p . 21, ll. 8-19). - 3 -Page: Previous 1 2 3 4 5 6 7 8 9 10 NextLast modified: November 3, 2007