Appeal No. 1997-1817
Application No. 08/139,693
1. A method for treating a body fluid related disease in a body
where a retrovirus is present in the body fluid and in cells infected by the
retrovirus, comprising the steps of:
administering as a Trigger Factor, a substance that stimulates the
region of proliferation control in the retrovirus in an infected cell to
increase proliferation rate, shorten cell life, and cause transition from an
asymptomatic period to a symptomatic period, to induce death of the
infected cells,
withdrawing the body fluid,
extracorporeally processing the withdrawn body fluid to kill,
inactivate, or remove the pathogenic microorganisms and preferably the
infected cells present in the body fluid, and
reinfusing the process body fluid
wherein the Trigger Factor is administered either prior to or in
parallel with the withdrawing and processing steps.
2. The method of claim 1 wherein the retrovirus is an HIV.
6. The method of claim 2 where the infected cell is a CD4
(positive) cell selected from the group consisting of T4 Helper
lymphocytes, macrophages and dendritic cells, into which the RNA of the
HIV has been transcribed and inserted as a provirus; wherein the body
fluid is a fluid selected from the group consisting of blood, lymphatic fluid
and cerebrospinal fluid; and wherein the Trigger Factor is a substance
selected from the group consisting of a biochemical substance and a
medicament.
7. The method of claim 6 where the biochemical substance
stimulates the provirus in the infected cell to replicate actively, subjects
the infected cell to programmed death, and promotes a transition from a
latent period to the AIDS related complex (ARC) period.
8. The method of claim 7 where the biochemical substance is a
substance selected from the group consisting of Tumor Necrosis Factor
(TNF) and anti-Fas antibody.
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