Ex Parte MIWA et al - Page 10




                Appeal No. 1997-1817                                                                                                            
                Application No. 08/139,693                                                                                                      


                Statement entered February 14, 1994 (Paper No. 4).  We note that Kroyer discusses                                               
                extracorporeal processing of body fluids to kill viruses, e.g., HIV, and undesired cells                                        
                therein, using heat and, optionally, adding virus-attenuating pharmaceuticals to the fluid                                      
                while it is in the extracorporeal device and/or exposing the fluid in the device to UV light,                                   
                etc.                                                                                                                            
                         In the event of any further action by the examiner, we urge the examiner to                                            
                structure his § 103 rejection consistent with the inquiries that are required for                                               
                establishing a factual basis to support a legal conclusion of obviousness as set forth in                                       
                Graham v. John Deere Co., 383 U.S. 1 , 17, 148 USPQ 459, 467 (1966), e.g., using the                                            
                model set forth in Section 706.02(j) of the Manual of Patent Examining Procedure                                                
                (MPEP) as follows:                                                                                                              
                         the examiner should set forth ... (1) the relevant teachings of the prior art                                          
                         relied upon, preferably with reference to the relevant column or page                                                  
                         number(s) and line number(s), where appropriate, (2) the difference or                                                 
                         differences in the claim over the applied reference(s), (3) the proposed                                               
                         modification of the applied reference(s) necessary to arrive at the claimed                                            
                         subject matter, and (4) an explanation why such proposed modification                                                  
                         would have been obvious to one of ordinary skill in the art at the time the                                            
                         invention was made.                                                                                                    
                Adherence to this model will ensure that the examiner considers the claims individually                                         
                and that the statement of the rejection will clearly and concisely apply the relevant                                           
                evidence of obviousness to the subject matter of an individual claim.                                                           




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