Appeal No. 1997-2336
Application No. 08/256,065
Claims 27, 30, 35, and 36 are representative of the subject matter on appeal and
read as follows:
27. A transdermal therapeutic application system useful for cancer prophylaxis
for applying through the skin of a person, an effective cancer prophylactic amount of an
active ingredient consisting essentially of
acetyl salicylic acid or a non-toxic pharmaceutically acceptable salt thereof or a
combination thereof;
said transdermal therapeutic application system comprising a matrix containing a
substance such that hydrolysis of acetyl salicylic acid is precluded or is at least greatly
reduced; and
said substance being selected from the group consisting of dioctyl cyclohexane,
dioctyl cyclohexane dissolved in n-heptane, glycerol ester of a partially hydrogenated
colophonium and dioctyl cyclohexane dissolved in n-heptane, and silicone oil.
30. A therapeutic method for preventing cancer in a person, comprising
administering through a transdermal therapeutic application system applied to the
skin of said person,
an effective cancer prophylactic amount of an active ingredient consisting
essentially of
acetyl salicylic acid or a non-toxic pharmaceutically acceptable salt thereof or a
combination thereof; and
said transdermal application system comprising a matrix containing a substance
such that hydrolysis of acetyl salicylic acid is precluded or is at least greatly reduced;(sic, .)
35. The therapeutic method of claim 30,
wherein said cancer prophylaxis is against tumor formation.
36. The therapeutic method of claim 35,
wherein said tumor formation prophylaxis is in the gastrointestinal tract.
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