Ex parte PANETTIERI et al. - Page 2



                     Appeal No. 1997-2756                                                                                                                                              
                     Application 08/242,728                                                                                                                                            



                                6.         A method of treating asthma and related systems in an individual suffering                                                                  
                     from asthma comprising administering to said individual an effective amount of an                                                                                 
                     antithrombin agent.                                                                                                                                               
                                The references relied upon by the examiner are:                                                                                                        
                     Murray et al. (Murray), “Receptor-Activated Ca Influx in Human Airway Smooth Muscle:                                                                              
                     Use of Ca Imaging and Perforated Patch-Clamp Techniques,” The American Physiological                                                                              
                     Society, Vol. 264 (Cell Physiol. 33), pp. C485-C490 (1993).                                                                                                       
                     Roth et al., “Inhibition of Receptor-Mediated Platelet Activation by Nedocromil Sodium,” J.                                                                       
                     Allergy Clin. Immunol. Vol. 91, No. 6, pp. 1217-1225 (1993).                                                                                                      
                                                                          Grounds of Rejection                                                                                         
                                                                                                                       1                                                               
                              Claims 3 and 6 stand rejected under 35 U.S.C. § 102(b) .  As evidence of anticipation,                                                                   
                   the examiner relies upon Murray.                                                                                                                                    
                              Claims 3 and 6 stand rejected under 35 U.S.C. § 103.  As evidence of obviousness, the                                                                    
                   examiner relies upon Roth.                                                                                                                                          
                              We affirm the rejection of claim 6 under 35 U.S.C. § 103 as obvious over Roth and                                                                        
                   reverse the rejections of claims 3 and 6 under 35 U.S.C. § 102(b) and claim 3 under 35 U.S.C.                                                                       
                   § 103.                                                                                                                                                              
                                                                                Background                                                                                             

                                The applicants' invention is described at pages 2-3 of the specification as being                                                                      
                     directed to a method of inhibiting cytosolic calcium release in human airway smooth                                                                               


                                1 In the Final Rejection of December 27, 1995 (Paper No. 7) the examiner rejected                                                                      
                     claims 1-3 and 6 under 35 U.S.C. § 102(b) or, in the alternative, under 35 U.S.C. § 103 as                                                                        
                     obvious over Murray.  The Examiner's Answer of November 6, 1996 (Paper No. 15) does                                                                               
                     not indicate that claims 3 and 6 are rejected under 35 U.S.C. § 103 as obvious over                                                                               
                     Murray.  Thus, we have limited our consideration of this rejection to the question of whether                                                                     
                     claims 3 and 6 are properly rejected under 35 U.S.C. § 102(b) as anticipated by Murray.                                                                           
                                                                                          2                                                                                            




Page:  Previous  1  2  3  4  5  6  7  8  9  10  Next 

Last modified: November 3, 2007