Appeal No. 1997-3328 Application No. 08/226,605 (specification, page 9). The preferred embodiment being subsequently described with respect to Fig. 4. The advantages described include "the leakage or diffusion of sample components is considerably decreased ... the noise of the detected signal is reduced ... [and] the sensitivity of the analytic system, that is the limit of detection, is increased" (specification, page 9). The examiner's rejection of claim 20 is based on Verheggen's description of a basic electrophoretic device and Harrison's teaching of electrokinetically introducing the sample "by applying a voltage (pt electrodes) between the separation channel and supply channel" (examiner's office action mailed May 16, 1995, Paper No. 3, page 5).5 The examiner also notes "Harrison also teaches that manipulation of channel geometry is possible to control where the applied potential drops. Kindly refer to Fig. 1; 1928, Results and Discussion, the two paragraphs" and concludes that "[i]t would have been obvious to one of ordinary skill in the art to 5 The final rejection (Paper No. 6) rejects then claim 12 (replaced in Paper No. 7 in favor of claim 20) by reference to "the office action mailed May 16, 1995" for an explanation of the rejection. 11Page: Previous 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 NextLast modified: November 3, 2007