Appeal No. 1997-3328 Application No. 08/226,605 representative of claims 2-11 and 19, and claim 20 (the independent article claim), as representative of claims 13-18 and 20, to decide the appeal on the respective rejections under 35 U.S.C. § 103 before us. The 35 U.S.C. § 103 rejection of claim 19. Claim 19 recites, 19. A method of introducing a sample into a electroporesis device,... which method comprises the step of electrokinetically injecting the sample as a sample plug into said electrolyte channel by applying an electric field across the supply and drain channels, wherein said electric field is applied for a time period which is at least long enough that the component of said sample having the lowest electrophoretic mobility migrates into the geometrically defined sample volume, such that the injected sample plug reflects the original sample composition. Appellants describe in the BACKGROUND OF THE INVENTION that "sample components from the feeders may diffuse into the capillary tube when the sample has already left the sampling position" whereby "at the detector there not only arrives a more or less broadened plug of injected sample fluid" but the "electrolyte in front and after or between individual plugs of sample fluid is 'polluted' with unpredictable amounts of sample components" (specification, page 2). The SUMMARY OF 4Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 NextLast modified: November 3, 2007