Ex parte MANZ et al. - Page 2




         Appeal No. 1997-3328                                                    
         Application No. 08/226,605                                              




                                   BACKGROUND                                    
              The appellants' invention relates to a method and a                
         device for controlled sample introduction in microcolumn                
         separation techniques (specification, p. 1).  A copy of the             
         claims under appeal is set forth in the appendix to the                 
         appellants' brief.2                                                     
              The prior art references of record relied upon by the              
         examiner in rejecting the appealed claims are:                          
         Verheggen et al. (Verheggen), “Simple Sampling Device for               
         Capillary Isotachophoresis and Capillary Zone                           
         Electrophoresis”, Journal of Chromatography, Vol. 452, pp.              
         615-622 (1988).                                                         
         Harrison et al. (Harrison), “Capillary Electrophoresis and              
         Sample Injection Systems Integrated on a Planar Glass Chip”,            
         Analytical Chemistry, Vol. 64, No. 17, pp. 1926-1932 (1992).            

              Claims 2-11 and 19 stand rejected under 35 U.S.C. § 103            
         as being unpatentable over Verheggen in view of Harrison.               
              Claims 13-18 and 20 stand rejected under 35 U.S.C. § 103           
         as being unpatentable over Verheggen in view of Harrison.3              

                                                                                
              2 In the appendix to the brief the second word "sampling" has been 
         omitted from each of claims 14-16.                                      
              3 The rejection of the claims under 35 U.S.C. § 112, second paragraph,
         has been overcome by appellants' amendment filed February 1, 1996 (Paper No.
                                        2                                        





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