Appeal No. 1997-3328 Application No. 08/226,605 current used to introduce the sample, which would lead one to conclude the sample was electrokinetically introduced", that Harrison teaches a "[s]ample is introduced electrokinetically by applying a voltage between the separation channel and supply channel" and that "[i]t would have been obvious to one of ordinary skill in the art to combine the method of Verheggen and Harrison because electrokinetic injection is conventional technique in the art of electrophoresis. Furthermore, both references deal with control of sample introduction and electrophoretic separation" (the office action of May 16, 1995, Paper No. 3, pages 3-4). Appellants state that "[t]he Examiner contends that such a solution to the problem is obvious because the period of applying the electric field is an art-recognized variable and it would have been obvious to optimize it. However, the Examiner does not claim that the references suggest to solve the problem recognized by Verheggen by optimizing the time period that the electric field is applied" (brief, page 7). The examiner notes that "maintaining the electric field for a period of time sufficient to allow for slower moving molecules to migrate is an art-recognized result-effective 6Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 NextLast modified: November 3, 2007