Interference No. 103,352
The subject matter in issue relates to a platinum (II) four-
coordinate complex which may be used as an anti-tumor
chemotherapy agent. The complex is more specifically defined by
the sole count of this interference as follows:
A platinum (II) four-coordinate complex having the formula:
wherein R and R are each alkyl carboxylato bearing a hydro-1 2
phobic radical function or, when linked together, are a
dicarboxylato bearing a hydrophobic radical function, and wherein
R and R are each amines of the formula:3 4
wherein R is selected from the group consisting of hydrogen,
s
alkyl, aryl, aralkyl, alkenyl, cycloalkyl, or cycloalkenyl having
between 1 and 20 carbon atoms; or wherein R and R , when linked3 4
together, are selected from the group consisting of cycloalkyl-
1,2-diamino having between about 3 and 7 carbon atoms, and alkyl-
vicinal-diamino having between about 3 and 7 carbon atoms, and
alkyl-vicinal-diamino having between about 2 and 12 carbon atoms;
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