Appeal No. 2000-0673 Application No. 08/960,276 Claims 56 and 58 read: 56. The method of claim 55 wherein the stent functions as a cathode in an anode/cathode pair and is immersed in an aqueous electrolyte solution including collagen and an electrical potential is established between the anode and cathode adequate to sustain electrodeposition of the collagen from the solution onto the metal surface of the stent. 58. The method of claim 56 wherein the potential is about 3 volts. In discussing the voltage to be applied between the electrodes (the cathode being the item to be coated), Vieth states at col. 5, line 65 to col. 6, line 3: Voltage and current requirements are dependent upon the dimensional parameters of a given system, such as the area of the support to be coated, the distance between electrodes, the temperature, and the concentration of materials and electrolytes in the aqueous mixture. Generally, it is preferable to use a relatively low voltage supply, such as from about 10 to 100 volts. The actual current requirements are quite small, generally from 1 to 10 amperes. Working at low voltages avoids an undesirable increase in temperature, which may denature the enzyme or its carrier, and also tends to favor electrophoresis over electrolysis. Voltages for a given application can be readily determined by simple trial and error. While the about 3 volts recited in claim 58 is lower than the voltage range disclosed by Vieth, supra, as generally preferable, we consider that it would have been obvious to use that voltage when electrodepositing collagen onto the stent of 6Page: Previous 1 2 3 4 5 6 7 8 9 10 11 NextLast modified: November 3, 2007