BRAKE v. SINGH - Page 32




                Interference 102,728                                                                                                          
                this instance since Brake 1 discloses the nucleotide sequence.  Tekamp-Olson                                                  
                Declaration 2, p. 4, para. 6c.  One skilled in the art need only compare manually, or                                         
                using a known computer program, the disclosed EGF nucleotide sequence with the                                                
                known amino acid sequence to correct the alignment.  Johnson Declaration, pp. 6-7;                                            
                Tekamp-Olson Declaration 2, p. 4, para. 6b.                                                                                   
                         Singh argues that (i) one skilled in the art would not have recognized the                                           
                nucleotide sequence in Brake 1 as EGF and would not have tried “to find two                                                   
                complementary sequences in what appeared to be a single 5' to 3' strand” (Singh                                               
                Opposition, Paper No. 30, p. 9); (ii) because Brake filed a continuation-in-part (CIP) of                                     
                Brake 1 which contained the amended EGF nucleotide sequence, Brake is estopped                                                
                from arguing that the new information in the second application was inherent in Brake 1                                       
                (id., p. 10); and (iii) if Brake had believed they were entitled to the benefit of Brake 1                                    
                they would have continued to prosecute that application rather than acquiescing to the                                        
                examiner’s rejection (id., pp. 10-11).  Singh relies on the declaration of Dr. Falkinham to                                   
                support many of these arguments.  We do not credit Dr. Falkinham’s testimony and find                                         
                these arguments unpersuasive.                                                                                                 
                         As discussed above Count 1 does not require a nucleotide sequence encoding                                           
                EGF.  Gene* encodes any non-Saccharomyces polypeptide.  Accordingly, we find that                                             
                each of these arguments fails to address a limitation present in the count.                                                   






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