LAGRANGE et al v. KONRAD et al - Page 44




                 Patent Interference No. 103,548                                                                                                 
                 with respect to the uptake data and the adequacy of the comparative testing, the hue                                            
                 and color data are just as inconclusive.                                                                                        
                         Lastly, we observe that, although Lagrange argues that the claimed C2-C4                                                
                 indolines are novel and unobvious, Lagrange's own specification makes no distinction                                            
                 between them and other preferred indolines (i.e., C0, C1, C2, and C4),. The Lagrange                                            
                 Patent (col. 2, lines 1-2) discloses that C0 is “particularly preferred”, although it is now                                    
                 precluded from the claims. Moreover, other than a description of the resulting hair colors                                      
                 associated with the use of each of the preferred indolines, Lagrange Patent '637 does                                           
                 not provide any of the comparative uptake test data on which Lagrange has relied upon                                           
                 to establish the nonobviousness of the C2-C4 indolines. None of the asserted benefits                                           
                 from using C2-C4 indolines are disclosed. According to Lagrange (paper no. 66,                                                  
                 paragraph 44), the selection of C2-C4 solves several problems in an unobvious way:                                              
                 · "they allow the production of blue-green shades instead of reddish shades";                                                   
                 · "they provide an improved uptake over the structurally closest 5,6-                                                           
                     dihydroxyindoline"; and,                                                                                                    
                 · "a person skilled in the art faced with the problem of providing blue-green tone                                              
                     dyestuffs would certainly not have been directed to use a 5,6-dihydroxyindoline and                                         
                     substitute it on the nitrogen atom".                                                                                        
                 However, we can find none of these asserted benefits in the specification of Lagrange’s                                         
                 patent. It would appear therefore that, as Konrad has argued (KOB 6, paragraph 19),                                             
                 Lagrange may not be in a position to now attach, for example, an unexpected uptake                                              
                 property to the claimed C2-C4 indolines. In re Lundberg, 253 F.2d 244, 247, 117 USPQ                                            


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