LAGRANGE et al v. KONRAD et al - Page 45




                 Patent Interference No. 103,548                                                                                                 
                 190, 192 (CCPA 1958).  We note that Lagrange does argue that the alleged unexpected                                             
                 uptake results "inherently flow from what is disclosed in Lagrange '637" and therefore                                          
                 should not be disregarded, citing In re Slocombe, 510 F.2d 1398, 1402; 184 USPQ 740,                                            
                 743 (CCPA 1975) and In re Davies, 475 F.2d 667, 177 USPQ 381 (CCPA 1973). LRB                                                   
                 16-17. But the lack of disclosure raises significant questions as to whether Lagrange                                           
                 can now rely on the uptake results set forth in the Cotteret Declarations. Nevertheless,                                        
                 this is not a matter we need to resolve.  As we have already discussed, based on our                                            
                 evaluation, the declaration evidence does not establish an unexpectedly improved                                                
                 uptake for the claimed C2-C4 indolines. The question of whether Lagrange can even rely                                          
                 on such data, in view of the lack of disclosure of that property, only adds to the                                              
                 weaknesses in the declaration evidence.                                                                                         
                         For the foregoing reasons, Lagrange has not met its burden of overcoming the                                            
                 prima facie case of obviousness.                                                                                                
                         Accordingly, Lagrange Preliminary Motions 2 and 3 are DENIED.                                                           
                         Lagrange has failed to meet its burden of establishing that the invention of                                            
                 Lagrange patent claim 29 and Lagrange reissue claims 1-21, 24-26 and 29 define a                                                
                 separate patentable invention with respect to any of Lagrange patent claims 1-21, 24-28                                         
                 and Konrad claims 1-14.  Accordingly, the designation of Lagrange patent claim 29 and                                           
                 Lagrange reissue claims 1-21, 24-26 and 29 as corresponding to the counts is                                                    
                 maintained. Consequently, given our determination that Konrad is entitled to priority of                                        
                 the subject matter of Counts 1-3, Lagrange is not entitled to a patent containing claim                                         




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