Ex Parte ARCHER et al - Page 12





                 Appeal No.  1995-2789                                                                                  
                 Application No. 07/788,114                                                                             


                  invention as it is claimed.”  This however, is merely a conclusion, not a fact-                       
                  based reasoned analysis of the claimed invention in view of appellants’                               
                  supporting disclosure.                                                                                
                        As set forth in In re Wands, 858 F.2d 731, 735, 736-37, 8 USPQ2d 1400,                          
                 1402, 1404 (Fed. Cir. 1988) the factors to be considered in determining whether                        
                 a claimed invention is enabled throughout its scope without undue                                      
                 experimentation include the quantity of experimentation necessary, the amount                          
                 of direction or guidance presented, the presence or absence of working                                 
                 examples, the nature of the invention, the state of the prior art, the relative skill of               
                 those in the art, the predictability or unpredictability of the art, and the breadth of                
                 the claims.  We find no analysis of the Wands factors by the examiner.  Instead,                       
                 we find only the examiner’s unsupported conclusion that the specification does                         
                 not enable the claimed invention.                                                                      
                        Similarly, the examiner argues (Answer, page 7) “it is questioned whether                       
                  one can even predictably isolate viable mutants of E. coli and B. subtilis which                      
                  are insensitive to feedback inhibition by threonine. … Thus, it would require                         
                  undue experimentation for the ordinary skilled artisan to either make or use the                      
                  claimed invention for E. coli and B. subtilis.”  The examiner, however, fails again                   
                  to provide a factual basis upon which to question the predictability of appellants’                   
                  claimed invention.                                                                                    
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