Ex parte GOKCEN et al. - Page 4




              Appeal No.1997-0466                                                                                          
              Application 08/154,158                                                                                       



              3.   Claims 16-22 and 61-70 stand rejected under 35 U.S.C. 103 over Pinnell and Longo in                     
              view of Baert.                                                                                               
                                                DECISION ON APPEAL                                                         
               35 U.S.C. 103                                                                                               
                     Claims 2, 53-55 and 72 stand rejected under 35 U.S.C. 103 over Pinnell.                               
                     In rejecting claims under 35 U.S.C. § 103, the examiner bears the initial burden of                   
              presenting a prima facie case of obviousness.  See In re Rijckaert, 9 F.3d 1531, 1532, 28                    
              USPQ2d 1955, 1956 (Fed. Cir. 1993).  A prima facie case of obviousness is established                        
              when the teachings from the prior art itself would appear to have suggested the claimed                      
              subject matter to a person of ordinary skill in the art.  In re Bell, 991 F.2d 781, 783, 26                  
              USPQ2d 1529, 1531 (Fed. Cir. 1993).   Furthermore, the conclusion that the claimed                           
              subject matter is prima facie obvious must be supported by evidence, as shown by some                        
              objective teaching in the prior art or by knowledge generally available to one of ordinary                   
              skill in the art that would have led that individual to combine the relevant teachings of the                
              references to arrive at the claimed invention.  See In re Fine, 837 F.2d 1071, 1074, 5                       
              USPQ2d 1596, 1598 (Fed. Cir. 1988). With this as background, we analyze the prior art                        
              applied by the examiner in the rejection of the claims on appeal.                                            
                     It is the examiner’s position that Pinnell clearly discloses compositions comprising                  
              collagenase and hyaluronidase.  The examiner suggests that the claimed recitations of                        

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