Ex parte PORTOGHESE - Page 7




               Appeal No. 1997-2204                                                                                             
               Application No. 08/440,989                                                                                       



                      Respecting the issue of indefiniteness under 35 U.S.C. § 112, second paragraph,                           
               we observe that “the definiteness of the language employed [in a claim] must be analyzed--                       
               not in a vacuum, but always in light of the teachings of the prior art and of the particular                     
               application disclosure as it would be interpreted by one possessing the ordinary level of                        
               skill in the pertinent art.”  In re Moore, 439 F.2d 1232, 1235, 169 USPQ 236, 238 (CCPA                          
               1971).                                                                                                           
                      In arguing that claim 21 does not comply with the definiteness requirement of 35                          
               U.S.C. § 112, second paragraph, the examiner sets forth a series of cryptic, staccato-like                       
               questions (Examiner’s Answer, page 5).  The examiner does not, however, provide any                              
               analysis of what the specification discloses or how persons skilled in the art would read                        
               claim 21 in light of the specification.  Absent such analysis, we will not sustain this rejection.               
                      Invoking the rubric of "undue experimentation" under 35 U.S.C. § 112, first                               
               paragraph, the examiner questions appellant's disclosure respecting "how to use"                                 
               mammalian tissue with blocked opiate receptors (Examiner’s Answer, page 4), the                                  
               breadth of "mammalian tissue" (Examiner’s Answer, page 5), and “how to make” certain                             
               embodiments encompassed by the claims (Examiner’s Answer, page 8).  By now it is well                            
               settled that the examiner bears the initial burden of providing reasons why a supporting                         
               disclosure does not enable a claim.  In re Marzocchi, 439 F.2d 220, 223, 169 USPQ 367,                           
               369 (CCPA 1971).  It has long been held that "[t]o be enabling, the specification of a patent                    
               must teach those skilled in the art how to make and use the full scope of the claimed                            


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