Appeal No. 1997-2393
Application No. 08/183,381
Parkhouse et al. (Parkhouse), “Antigens of parasitic helminths in diagnosis,
protection and pathology,” Parasitology, Vol. 99, p. S5-S19 (1989)
Good2, “A malaria vaccine strategy based on the induction of cellular immunity”
Immunology Today, Vol. 13, pp. 126-130 (1992)
Audibert et al. (Audibert), “Adjuvants: current status, clinical perspectives and future
prospects,” Immunology Today, Vol. 14, pp. 281-284 (1993)
Letvin, “Vaccines against human immunodeficiency virus – progress and
prospects,” The New England Journal of Medicine, Vol. 329, No. 19, pp. 1400-1405
(1993)
The references relied upon by appellants are:
Nepom et al. (Nepom), “Induction of immunity to a human tumor marker by in vivo
administration of anti-idiotypic antibodies in mice,” Proc. Natl. Acad. Sci. USA, Vol.
81, pp. 2864-2867 (1984)
McNamara et al. (McNamara), “Monoclonal idiotope vaccine against streptococcus
pneumoniae infection,” Science, Vol. 226, pp. 1325-1326 (1984)
Kennedy et al. (Kennedy), “Antibody to Hepatitis B virus induced by injecting
antibodies to the idiotype,” Science, Vol. 223, pp. 930-931 (1984)
Stein et al. (Stein), “Neonatal administration of idiotype or antiidiotype primes for
protection against Escherichia coli K13 infection in mice,” Journal of Exp. Med.,
Vol. 160, pp. 1001-1011 (1984)
Raychaudhuri et al. (Raychaudhuri), “Tumor-specific idiotype vaccines, analysis of
the tumor-related network response induced by the tumor and by internal image
antigens (Ab2ß), J. Immunology, Vol. 139, pp. 271-278 (1987)
Dalgleish et al. (Dalgleish), “Anti-idiotypic antibodies as immunogens: idiotype-
based vaccines,” Vaccine, Vol. 6, pp. 215-220 (1988)
Kresina et al. (Kresina), “Antiidiotypic antibody vaccine in murine Schistosomiasis
mansoni comprising the internal image of antigen,” J. Clin. Invest. Vol. 83, pp. 912-
920 (1989)
2 We note that the examiner identifies the author of this reference as Riley.
However, Riley is the author of the “Comment by Eleanor Riley” which follows (at
pages 129-130), and comments on, the Good article (at pages 126-130). The
author of the reference is correctly identified herein above.
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