Appeal No. 1997-3503
Application No. 08/172,866
inclined surface of said reaction vessel through said analyte
and said immunological substance;
(c) arranging a magnet outside said reaction vessel such that
magnetic particles which are not agglomerated on the
inclined surface are caused by the magnetic field to be
moved along the inclined surface to reach a bottom portion
thereof, while magnetic particles agglomerated on the
inclined surface are not moved by the magnetic field,
thereby forming a particle pattern concentrated at the center
of a lower end portion of the reaction vessel in the absence
of said analyte, and forming a particle pattern uniformly
spread on the inclined surface in the presence of said
analyte; and
(d) determining the presence of the absence of the analyte on
the basis of the particle pattern of the magnetic particles
formed on the inclined surface by the action of the magnetic
field.
The references relied upon by the examiner are:
Rosenfield et al. (Rosenfield) 4,328,183 May 4, 1982
Ikeda et al. (‘813) 4,416,813 Nov. 22, 1983
Forrest 4,438,068 Mar. 20, 1984
Ikeda et al. (‘622) 4,582,622 Apr. 15, 1986
Sakuma 4,661,460 Apr. 28, 1987
Asakura et al. (Asakura) J5 6142-259 Nov. 6, 19812
Ikeda et al. (‘061) EP 0 233 061 Aug. 19, 1987
2 The examiner relied upon an English language translation of this document.
3
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