Ex Parte NAKAMURA et al - Page 8


                    Appeal No.  1997-3503                                                                                                   
                    Application No.  08/172,866                                                                                             

                    present invention cannot be expected from the cited references.  Where a                                                
                    gravitational force is utilized as in Sakuma, it is not possible to obtain an [sic]                                     
                    desirable sensitivity as in the present invention.”                                                                     
                            The examiner argues (Answer, page 12) that “[o]ne of ordinary skill in the                                      
                    art would have known that when a magnet is used to replace the force of gravity,                                        
                    it should be placed at the bottom of the reaction vessel…” and one would                                                
                    “certainly have expected that use of a magnet for precipitation in place of gravity                                     
                    would have shortened the precipitation time considerably.  The clearly                                                  
                    distinguishable positive or negative pattern would have naturally resulted from                                         
                    the use of the magnet.” We remind appellant, as set forth in In re Freeman, 474                                         
                    F.2d 1318, 1324, 177 USPQ 139, 143 (CCPA 1973):                                                                         
                            In order for a showing of “unexpected results” to be probative                                                  
                            evidence of non-obviousness, it falls upon the applicant to at least                                            
                            establish: (1) that there actually is a difference between the results                                          
                            obtained through the claimed invention and those of the prior art,                                              
                            and (2) that the difference actually obtained would not have been                                               
                            expected by one skilled in the art at the time of the invention.                                                
                    Here appellants have not established that the difference actually obtained by the                                       
                    use of a magnet as set forth in the examiner’s rejection would not have been                                            
                    expected by one skilled in the art at the time of the invention.  As explained by                                       
                    the examiner (Supplemental Answer, page 2), “none of the references used for                                            
                    rejection of the claims suggests the use of centrifugation for rapid precipitation.”                                    
                    Accordingly, we are not persuaded by appellants’ arguments and evidence of                                              
                    unexpected results.                                                                                                     

                                                                                                                                            
                    11 Executed, October 26, 1993.                                                                                          

                                                                     8                                                                      



Page:  Previous  1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  Next 

Last modified: November 3, 2007