Appeal No. 1997-3811 Page 2
Application No. 08/357,845
BACKGROUND
Appellants' invention relates to a method of separating
enantiomers of a racemic compound mixture from each other
using
high-speed countercurrent chromatography involving several
particularly specified steps. An understanding of the
invention can be derived from a reading of exemplary claim 1,
which is reproduced below.
1. A method for separating a quantity of the (+)
and (-) enantiomers of a racemic compound mixture
from each other using high-speed countercurrent
chromatography, comprising:
(a) adding a chiral selector to a first liquid
phase of two pre-equilibrated immiscible liquid
phases and charging a countercurrent chromatographic
centrifuge column with said first liquid phase,
thereby producing a countercurrent chromatographic
centrifuge column charged with said chiral selector
and said first liquid phase;
(b) introducing said racemic compound mixture
into said countercurrent chromatographic centrifuge
column thus charged with said chiral selector and
said first liquid phase; and
(c) passing a second liquid phase through said
countercurrent chromatographic centrifuge column
thus charged with said mixture, said chiral selector
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