Appeal No. 1997-3811 Page 5 Application No. 08/357,845 Rejections under 35 U.S.C. § 102 The examiner has the initial burden of establishing a prima facie case of anticipation by pointing out where all of the claim limitations are described in a single reference. See In re Spada, 911 F.2d 705, 708, 15 USPQ2d 1655, 1657 (Fed. Cir. 1990); In re King, 801 F.2d 1324, 1327, 231 USPQ 136, 138-39 (Fed. Cir. 1986). This the examiner has not done. All of the claims on appeal require a method of separating a specified quantity of the (+) and (-) enantiomers of a racemic compound mixture from each other using high-speed countercurrent chromatography. The method of claim 1, the sole independent claim on appeal, includes the following steps: (a) adding a chiral selector to a first liquid phase of two pre-equilibrated immiscible liquid phases and charging a countercurrent chromatographic centrifuge column with said first liquid phase;Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 NextLast modified: November 3, 2007