Ex Parte VAN ASSCHE et al - Page 10


                 Appeal No. 1997-4272                                                                                   
                 Application No. 08/429,053                                                                             

                                              New Ground of Rejection                                                   
                        Under the provisions of 37 CFR § 1.196(b), we make the following new                            
                 ground of rejection:  claim 24 is rejected under 35 U.S.C. § 112, second                               
                 paragraph, as indefinite.  As discussed above, claim 24 is open to two                                 
                 interpretations, both of which appear plausible in light of the specification and                      
                 prosecution history.  Since we cannot determine the metes and bounds of the                            
                 claim, we conclude that claim 24 is indefinite.  See Miles Laboratories Inc. v.                        
                 Shandon Inc., 997 F.2d 870, 875, 27 USPQ2d 1123, 1126 (Fed. Cir. 1993) (“The                           
                 test for definiteness is whether one skilled in the art would understand the                           
                 bounds of the claim when read in light of the specification.”).  See also In re                        
                 Morris, 127 F.3d 1048, 1054, 44 USPQ2d 1023, 1029 (Fed. Cir. 1997) (“It is the                         
                 applicants’ burden to precisely define the invention, not the PTO’s.  See                              
                 35 U.S.C. § 112, ¶ 2. . . .  [T]his section puts the burden of precise claim drafting                  
                 squarely on the applicant.”).                                                                          
                                                     Other Issues                                                       
                        As noted above, claim 24 may properly be construed to read on a                                 
                 monoclonal antibody directed against any SPS enzyme.  If so, claim 24 would                            
                 read on the spinach SPS-specific monoclonal antibodies disclosed by Walker.                            
                 See page 520, right-hand column (“Three stable independent hybridoma clones                            
                 . . . were isolated which produce antibodies directed against spinach leaf sucrose                     
                 phosphate synthase.”).  The examiner should consider whether Walker                                    
                 anticipates claim 24.                                                                                  



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