Ex Parte LANGE et al - Page 10




              Appeal No. 1998-0900                                                                                        
              Application No. 08/290,047                                                                                  

                     The examiner does not offer an explanation as to how claim 1 directed to                             
              "Polymerisable enantiomers of optically active dipeptides" should be read as a                              
              composition which include mixtures of various optically active compounds.  However,                         
              our reading of Wagner would suggest that this question is not relevant to the outcome                       
              of this aspect of the appeal.                                                                               
                     Basic to the examiner's position is that one of ordinary skill in this art would                     
              recognize the presence of an asymmetric carbon as indicating the existence of optical                       
              active isomers of the prior art dipeptides.  However, as appellants point out, the                          
              disclosed compounds of Wagner, on which the examiner relies (Answer, page 10), do                           
              not exhibit asymmetric carbons.  Both carbons, which are asymmetric in the claimed                          
              compounds, are described as methylene (CH2) by Wagner. (Brief, pages 4-5).  Thus,                           
              there is nothing about this portion of Wagner which would suggest optically active                          
              isomers, and the examiner has provided no evidence which would reasonably suggest                           
              the modification of the dipeptides of Wagner in a manner to arrive at the claimed                           
              invention.                                                                                                  
                     On this record, we find that the examiner has failed to provided evidence which                      
              would reasonably established that the claimed subject matter would have been prima                          
              facie obvious within the meaning of 35 U.S.C. § 103 at the time of the invention.  The                      
              examiner's rejection of the claims is fatally defective since it does not properly account                  
              for and establish the obviousness of the subject matter as a whole.  Where the                              
              examiner fails to establish a prima facie case, the rejection is improper and will be                       
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