Appeal No. 1999-1676 Application No. 08/452,228 Claims 1 and 3 are illustrative of the subject matter on appeal and are reproduced below: 1. An isolated protein nucleic acid molecule consisting of a nucleotide sequence that encodes a protein having the following amino acid sequence: NH2-Val Pro Ile Gln Lys Val Gln Ser Asp Thr Lys Thr Leu Ile Lys Thr Ile Val Thr Arg Ile Asn Asp Ile Ser His Thr Gln Ser Val Ser Ser Lys Gln Arg Val Thr Gly Leu Asp Phe Ile Pro Gly Leu His Pro Val Leu Thr Leu Ser Gln Met Asp Gln Thr Leu Ala Ile Tyr Gln Gln Ile Leu Ile Asn Leu Pro Ser Arg Asn Val Ile Gln Ile Ser Asn Asp Leu Glu Asn Leu Arg Asp Leu Leu His Leu Leu Ala Phe Ser Lys Ser Cys His Leu Pro Leu Ala Ser Gly Leu Glu Thr Leu Glu Ser Leu Gly Asp Val Leu Glu Ala Ser Leu Tyr Ser Thr Glu Val Val Ala Leu Ser Arg Leu Gln Gly Ser Leu Gln Asp Met Leu Trp Gln Leu Asp Leu Ser Pro Gly Cys-COOH (SEQ ID NO: 2). 3. A recombinant DNA vector comprising a nucleic acid molecule of [c]laim 1. The references relied upon by the examiner are: Martial et al. (Martial), “Human Growth Hormone: Complementary DNA Cloning and Expression in Bacteria,” Science, Vol. 205, pp. 602-607 (1979) Zhang et al. (Zhang), “Positional cloning of the mouse obese gene and its human homologue,” Nature, Vol. 372, pp. 425-429 (1994) GROUNDS OF REJECTION Claims 1 and 2 stand rejected under 35 U.S.C. § 103, as being unpatentable over Zhang. Claims 3-8 stand rejected under 35 U.S.C. § 103, as being unpatentable over Zhang in view of Martial. We reverse. 2Page: Previous 1 2 3 4 5 6 7 8 9 10 NextLast modified: November 3, 2007