Ex parte BASINSKI et al. - Page 3


                 Appeal No. 1999-1676                                                                                    
                 Application No. 08/452,228                                                                              
                                                     DISCUSSION                                                          
                        In reaching our decision in this appeal, we have given careful consideration                     
                 to the appellants’ specification and claims, and to the respective positions                            
                 articulated by the appellants and the examiner.  We make reference to the                               
                 examiner’s Answer1 for the examiner’s reasoning in support of the rejection.  We                        
                 further reference appellants’ Brief2 for the appellants’ arguments in favor of                          

                 patentability.                                                                                          
                 BACKGROUND                                                                                              
                        The present invention is based on the discovery of an obesity gene cloned                        
                 from Rhesus monkey adipose tissue.  Specification, page 2.  According to the                            
                 specification (page 3) “[t]he invention is drawn to isolated nucleic acid molecules                     
                 consisting of a nucleotide sequence that encodes a protein having the amino acid                        
                 sequence of SEQ ID NO:2.”                                                                               
                        According to the specification (Example 1) the obesity gene from Rhesus                          
                 monkey was obtained by polymerase chain reaction amplification methods using                            
                 degenerate primers “designed based on the published amino acid sequence of                              
                 [the] region flanking the human ob gene.”                                                               
                        While we note appellants’ statement (Brief, page 2) that there are no related                    
                 appeals and interferences, we make reference to Appeal No. 1999-1702                                    
                 (Application No. 08/445,305).  Claim 1 at issue in Appeal No. 1999-1702 is drawn                        
                 to an isolated protein of the formula: SEQ ID NO:1 or a pharmaceutically acceptable                     
                                                                                                                         
                 1 Paper No. 15, mailed October 14, 1998.                                                                
                 2 Paper No. 13, received December 22, 1997.                                                             

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