Ex parte BASINSKI et al. - Page 5


                 Appeal No. 1999-1676                                                                                    
                 Application No. 08/452,228                                                                              
                        In response appellants argue (Brief, bridging paragraph, pages 4-5) with                         
                 reference to In re Bell, 991 F.2d 781, 26 USPQ2d 1529 (Fed. Cir. 1993) that “[t]he                      
                 fact that methods exist which might allow one to clone a rhesus ob cDNA, however,                       
                 is irrelevant as to whether that particular cDNA is obvious. … Similarly, [a]pplicants                  
                 do not claim a method of isolating an ob cDNA, but rather claim the ob cDNA itself.”                    
                 Appellants appear to argue that Bell, see also In re Deuel, 51 F.3d 1552, 34                            
                 USPQ2d 1210 (Fed. Cir. 1995), stands for the proposition that it is per se error to                     
                 rely upon so-called methodology in determining the patentability of claims directed                     
                 to a product.  In this regard, we note that since the decisions in Bell and Deuel, our                  
                 appellate reviewing court has made it clear that there are no per se rules of                           
                 obviousness or nonobviousness.  In re Ochiai, 71 F.3d 1565, 1572, 37 USPQ2d                             
                 1127, 1133 (Fed. Cir. 1995)(“reliance on per se rules of obviousness is legally                         
                 incorrect”).  Accord, In re Brouwer, 77 F.3d 422, 425, 37 USPQ2d 1663, 1666                             
                 (Fed. Cir. 1996).                                                                                       
                        Further, such a per se approach would be in conflict with long standing                          
                 precedent as to the relevance of the method of making a product to the                                  
                 obviousness of the product.  Note In re Payne, 606 F.2d 303, 314, 203 USPQ 245,                         
                 255 (CCPA 1979), citing In re Hoeksema, 399 F.2d 269, 274, 158 USPQ 596, 601                            
                 (CPA 1968)(“[a]n invention is not ‘possessed’ absent some known or obvious way                          
                 to make it”).  In a similar manner, the court in In re O’Farrell, 853 F.2d 894, 902, 7                  
                 USPQ2d 1673, 1680 (Fed. Cir. 1988), in considering the Polisky reference relative                       
                 to the rejected claims stated “Polisky contained detailed enabling methodology for                      



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