Ex parte CAREY et al. - Page 10




            Appeal No. 1999-1703                                                                              
            Application No. 08/313,194                                                                        



            determine whether the examiner has met his burden of proof by advancing acceptable                
            reasoning inconsistent with enablement.   Factors to be considered by the examiner in             
            determining whether a disclosure would require undue experimentation have been                    
            summarized by the board in Ex parte Forman, [230 USPQ 546, 547 (BdPatAppInt 1986)].               
                   In our view, the examiner has failed to establish a prima facie case of lack of            
            enablement by advancing acceptable reasoning inconsistent with enablement, such as                
            providing evidence that there are various unrelated compounds which are classified as             
            known aldose reductase inhibitor or hypoglycaemic agents and that those of skill in the art       
            would not readily understand which species would have the claimed effect.   The examiner          
            has failed to enumerate and analyze the relevant Forman factors to  determine whether the         
            disclosure would require undue experimentation on the part of one of ordinary skill in the        
            art.   Thus, the examiner has failed to meet the burden of putting forward evidence               
            inconsistent with enablement.  Accordingly, the rejection of claim 13 for lack of enablement      
            is reversed.                                                                                      


                                               CONCLUSION                                                     
                   The rejection of claims 1-5 and 13 under 35 U.S.C. § 103(a) as obvious over                
            applicants' admissions (specification pages 1-3) in view of Bagley is reversed.   The             



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