Interference 103,579
amylose formation” (Hofvander Claims 7, 12-16, and 19-20), and
to transgenically modify the genome of potato plant cells by
genetic engineering (Visser’s Claim 1) so to grow and regenerate
potato plants with “tubers containing essentially amylose
free starch” (Visser’s Claim 1) by “substantially inhibit[ing]
. . . expression of potato . . . [GBSS]” (Visser’s Claim 15).
Hofvander’s claims designated as corresponding to the count also
include methods “for tuber-specific expression of a gene product
in potato, comprising transforming said potato with a DNA
molecule comprising an isolated promoter from the potato gene
coding for . . . GBSS . . .” (Hofvander’s Claims 21 and 23) and
methods “of suppressing amylose formation in potato . . .
comprising a fragment of the potato gene which codes for
formation of . . . GBSS . . . inserted in the antisense
direction, wherein said fragment has the nucleotide sequence of
SEQ ID No. 1" (Hofvander’s Claim 50).
(2) Preliminary matters
(a) Hofvander’s SEQ ID Nos. 1, 2, 3, 4, and 5
Hofvander’s PCT publication, published July 9, 1992
(Hofvander’s PCT application, filed December 20, 1991) and
Hofvander’s involved application, as filed November 24, 1993
(HR 275-316), characterize SEQ ID No. 5 as follows (HR 302):
SEQ ID No. 5
-30-
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