Ex Parte KLIPPEL et al - Page 4




             Appeal No. 2001-1378                                                                                    
             Application No. 08/832,571                                                                              

             Examiner's Answer for the examiner=s complete reasoning in support of the rejection,                    
             and to the appellants’ Brief for the appellants’ arguments thereagainst. As a                           
             consequence of our review, we make the determinations which follow.                                     


             Claim Interpretation                                                                                    
                    Our appellate reviewing court stated in Pandit Corp. v. Dennison Mfg. Co.,                       
             810 F.2d 1561, 1567-1568, 1 USPQ2d 1593, 1597 (Fed. Cir.), cert denied, 481 U.S.                        
             1052 (1987):                                                                                            
                           Analysis begins with a key legal question -- what is the                                  
                           invention claimed?  Courts are required to view the claimed                               
                           invention as a whole.  35 U.S.C. 103.  Claim interpretation,                              
                           in light of the specification, claim language, other claims and                           
                           prosecution history, is a matter of law and will normally                                 
                           control the remainder of the decisional process.  [Footnote                               
                           omitted.]                                                                                 
             To that end, we also note that during ex parte prosecution, claims are to be given their                
             broadest reasonable interpretation consistent with the description of the invention in the              
             specification.  In re Zletz, 893 F.2d 319, 321, 13 USPQ2d 1320, 1322 (Fed. Cir. 1989).                  
                    Claim 1 is directed to an isolated polynucleotide sequence comprising:                           
                    (a) a first nucleotide sequence comprising a sequence selected from the group                    
             consisting of:                                                                                          
                    (i) a nucleotide sequence encoding the p110 of PI 3-kinase protein and                           




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