Ex Parte TAKLE et al - Page 3


                  Appeal No.  2001-1498                                                            Page 3                   
                  Application No.   08/912,378                                                                              
                  Merchat et al. (Merchat), “Meso-substituted Cationic Porphyrins as Efficient                              
                  Photosensitizers of Gram-positive and Gram-negative Bacteria,” J.                                         
                  Photochemistry and Photoiology B: Biology, Vol. 32, pp. 153-157 (1996)                                    
                                              GROUNDS OF REJECTION                                                          
                         Claims 9-12 and 14 stand rejected under 35 U.S.C. § 102(b) as                                      
                  anticipated by Gibbs.                                                                                     
                         Claim 13 stands rejected under 35 U.S.C. § 102(b) as anticipated by or, in                         
                  the alternative, under 35 U.S.C. § 103 as obvious over Gibbs.                                             
                         Claims 1-4 stand rejected under 35 U.S.C. § 103 as being unpatentable                              
                  over any one of Takle, George or Sessler in view of Merchat.                                              
                         Claims 4-8 stand rejected under 35 U.S.C. § 103 as being unpatentable                              
                  over any one of Takle, George or Sessler in view of Merchat and further in view                           
                  of Ortigao, Yuan, Kobayashi and Winnacker.                                                                
                         Claims 15, 16 and 33 stand rejected under 35 U.S.C. § 103 as being                                 
                  unpatentable over any one of Gibbs or Ortigao in view of Yuan, Kobayashi and                              
                  Winnacker.                                                                                                
                         We reverse.                                                                                        
                                                      DISCUSSION                                                            
                  THE REJECTION UNDER 35 U.S.C. § 102:                                                                      
                  According to the examiner (Answer, page 6), Gibbs “teaches compositions                                   
                  comprising calf thymus DNA, … ionically bound and intercalated by synthetic                               
                  porphyrins….”  In addition, the examiner finds (Answer, page 16), “[a]ny nucleic                          
                  acid or nucleic acid derivative can be used in the disclosed porphyrin                                    
                  compositions and delivered to bacterial cells using the disclosed method.”                                







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