Appeal No. 2001-2168 Application No. 09/083,307 response against transformed, infected or diseased tissue. Appellant’s invention is useful in the treatment of cancer. According to appellant’s invention, the patient’s blood is pumped through a filter having a cutoff of 120,000 daltons1 to remove those blood components having molecular weights equal to or less than the filter cutoff and comprised of immunosuppressive components. The removal of the immunosuppressive components by the filter is said to improve the patient’s immune response to the disease or infection being treated. A copy of the appealed claims is appended to appellant’s brief. The following references are relied upon by the examiner as evidence of obviousness in support of the rejections under 35 U.S.C. § 103: Lentz 4,708,713 Nov. 24, 1987 Okarma et al. 5,523,096 Jun. 04, 1996 (Okarma) Wolpe 5,861,483 Jan. 19, 1999 1 The manner in which the filter is disclosed and claimed in appellant’s application presupposes a predetermined relationship between the size of the components in the blood and the molecular weight of those components (e.g., the smaller the size, the smaller the molecular weight). We understood that it is customary in the art to define the size of membrane filters or ultra filters, as they are also called, in terms of the molecular weight of the blood components passed by the filter. 2Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 NextLast modified: November 3, 2007