Appeal No. 2001-2168 Application No. 09/083,307 Chen et al., “Soluble TNF-alpha receptors are constitutively shed and downregulate adhesion molecule expression in malignant gliomas.” Journal of Neuropathology and Experimental Neurology, vol. 56, no. 5 (May 1997) pp.541-550 The appealed claims stand rejected under § 103 as follows: 1. Claims 1-4, 8, 9, 16, 18-20 and 22 as unpatentable over Lentz; 2. Claim 21 as unpatentable over Lentz in view of Okarma; 3. Claim 7 as unpatentable over Lentz in view of Chen; and 4. Claims 5, 6, 10-15, 17 and 23 as unpatentable over Lentz in view of Wolpe. Reference is made to the examiner’s answer for details of the foregoing rejections. With regard to the first rejection listed above (i.e., the rejection based on Lentz alone), we note that claims 1- 4, 9 and 18-20 have been grouped together by appellant for determining the issue of patentability (see page 4 of the main brief). This group of claims has been identified as group 12 on page 11 of the main brief. Under these circumstances, we are authorized under 37 CFR 2 On page 4 of the main brief, roman numerals are used to 3Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 NextLast modified: November 3, 2007