ELI LIILY & CO. vs. CAMERON et al - Page 10




                                                                                              Interference No. 104,101                   
                                                                                                                Page 10                  
                F19.    Mr. Cullinan’s testimony fails to specifically identify the source of the starting material,                     
                i.e., the “hydroxy” compound that is said to undergo reduction.  Moreover, Mr. Cullinan’s                                
                testimony fails to specifically explain how he confirmed the structure of the starting material                          
                undergoing reduction.                                                                                                    


                F20.    Mr. Cullinan testifies that he submitted the product from the above chemical reduction                           
                reaction, described on page 261 of his laboratory notebook (EX 1201, Bates No. 3012) for mass                            
                spectroscopy analysis, proton NMR analysis and I.R. analysis.  (EX 1152, ¶ 34, EX 1211, Bates                            
                No. 3069).  Mr. Cullinan states that the results of these analyses helped confirm that he had made                       
                a compound having the following structure:                                                                               









                (EX 1152, ¶ 34).  The above depicted structure is within the scope of Count 2.                                           


                F21.    Mr. Cullinan’s testimony fails to explain how the “mass spectroscopy analysis, proton                            
                NMR analysis and I.R. analysis helped to confirm” that he had made the identified compound.                              
                Specificlly, Mr. Cullinan failed to cite and/or explain the underlying data for his conclusion that                      
                he made the specific structure depicted on PC 469,307 (Bates No. 3069).  Additionally, Mr.                               







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