Appeal No. 1998-0667 Page 3
Application No. 081280,306
The references relied upon by the examiner are:
Lowy et al. (Lowy) 5,437,951 Aug. 1, 1 995
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Free System," Science, Vol. 220, pp. 725-727 (May 1 3, 1983)
Hanvey et al. (Hanvey), "Antisense and Antigene Properties of Peptide Nucleic Acids,"
Science, Vol. 258, pp. 1481-1485 (November 27, 1992)
Sandig et al. (Sandig), "Generation of DNA-Packaging Proteins by Overexpression in
the Baculovirusllnsect Cell System," 12th Meeting of the European Society for Animal
Cell Technology (May 17-21, 1993)
Haynes et al. (Haynes), "Mutations in the Putative Calcium-Binding Domain of
Polyomavirus VP1 Affect Capsid Assembly," Journal of Virolosv, Vol. 67, No. 5, pp.
2486-2495 (1 993)
Culver et al. (Culver), "Gene Therapy for Cancer," Trends in Genetics, Vol. 10, No. 5,
pp. 174-1 78 (May 1994)
Wu-Pong, "Oligonucleotides: Opportunities for Drug Therapy and Research,"
Pharmaceutical Technoloqv, Vol. 18, pp. 102, 104, 106, 108, 1 10-1 12, 1 14
(October 1 9'94)
Wagner, "Gene Inhibition Using Antisense Oligodeoxynucleotides," Nature, Vol. 372,
pp. 333-335 (November 24, 1994)
Miller et al. (Nliller 1994), "Gene Transfer and Antisense Nucleic Acid Techniques,"
Parasitolosv Todav, Vol. 10, No. 3, pp. 92-97 (1994)
Hodgson, "Advances in Vector Systenis for Gene Therapy," Expert Opinion in
~herapeutic Patents, Vol. 5, No. 5, pp. 459-468 (May 1995)
Marshall, "Gene Therapy's Growing Pains," Science, Vol. 269, pp. 1050-1 055
(August 25, 1995)
Miller et al. (Miller 1995), "Targeted Vectors for Gene Therapy," FASEB Journal, Vol. 9,
pp. 190-1 99 (February 1995)
Stull et al. (Stull), "Antigene, Ribozynie and Aptamer Nucleic Acid Drugs: Progress and
Prospects," Pharmaceutical Research, Vol. 12, No. 4, pp. 465-483 (1 995)
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