Ex Parte CIMA et al - Page 4




          Appeal No. 1998-2813                                                        
          Application No. 08/463,203                                                  


          Regarding the examiner's rejection of claims 19, 31, 32/19                  
          and 36/19 under 35 U.S.C. § 102(e) as being anticipated by Fink,            
          our reading of the Fink patent indicates that it is directed to             
          the fabrication of prosthetic implants to replace bone (i.e.,               
          medical devices) that are formed using various free-form                    
          manufacturing techniques (col. 4, line 3, et. seq.) including               
          selective laser sintering and 3D-printing.  These devices are               
          indicated (col. 5, lines 23-34) as being constructed to maximize            
          "the rate and quality of cell-mediated hard tissue healing" and             
          to "optimize the rate of healing by incorporating the patient's             
          own bone-producing cells into the implant" (emphasis added).                
          Fink notes (col. 3, line 7, et. seq.) that the most important               
          physical properties of the implant are the volume and size of the           
          pores within the implant, since such factors strongly influence             
          not only the strength of the implant but also the rate of                   
          resorption and cellular colonization.  In this regard, it is                
          indicated that pores of "at least" 200-300 micrometers in                   
          diameter are necessary in osteoconductive materials to permit               
          ingrowth of vasculature and osteogenic cells.  An example of an             
          implant material (col. 3, lines 23-25) is said to be composed of            
          a network of interconnecting pores in the range of approximately            
          200 µm diameter.  While Fink generally discloses the use of                 
          resorbable, biocompatible ceramic materials to construct the                

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