Ex Parte CIMA et al - Page 16




          Appeal No. 1998-2813                                                        
          Application No. 08/463,203                                                  


          Claims                                                                      
          19.  A medical device for tissue regeneration formed using a                
          solid free-form fabrication method comprising a matrix of                   
          successive layers of biocompatible polymeric material having                
          interconnected pores extending throughout the matrix suitable of            
          seeding or ingrowth of cells.                                               

          21.  A medical device for bone regeneration formed using                    
          three dimensional printing comprising a matrix of successive                
          layers of biocompatible composite material having interconnected            
          pores extending throughout the matrix suitable for seeding or               
          ingrowth of cells, having pore size of at least five to forty               
          microns in diameter,                                                        
          wherein the methods comprises                                               
          a) spreading a first dispersion of a resorbable powder                      
          selected from the group consisting of calcium phosphate,                    
          hydroxyapatite, and calcium carbonate onto a bed,                           
          b) printing a layer comprising a second dispersion of                       
          biocompatible polymer or composite powder in a solvent which                
          binds the first powder to the second biocompatible polymer or               
          composite powder at locations where it is desired to have walls,            
          and                                                                         
          c) repeating step b until the desired matrix is made.                       


















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