Appeal No. 1999-2634 Application No. 08/108,606 Soderlind or Gregory and Myers in further view of Evans 2. Claim 11 stands rejected under 35 U.S.C. ' 103 over Evans 1 in view of Svennerholm, and Soderlind or Gregory and Myers in further view of Evans 3. In rejecting claims under 35 U.S.C. ' 103, the examiner bears the initial burden of presenting a prima facie case of obviousness. See In re Rijckaert, 9 F.3d 1531, 1532, 28 USPQ2d 1955, 1956 (Fed. Cir. 1993). A prima facie case of obviousness is established when the teachings from the prior art itself would appear to have suggested the claimed subject matter to a person of ordinary skill in the art. In re Bell, 991 F.2d 781, 783, 26 USPQ2d 1529, 1531 (Fed. Cir. 1993). An obviousness analysis requires that the prior art both suggest the claimed subject matter and reveal a reasonable expectation of success to one reasonably skilled in the art. In re Vaeck, 947 F.2d 488, 493, 20 USPQ2d 1438, 1442 (Fed. Cir. 1991). With this as background, we analyze the prior art applied by the examiner in the rejection of the claims on appeal. Claim 7 According to the examiner, (Paper No. 16, page 4) Evans et al teach a method for producing an E. coli bacterial strain expressing colonization factor antigens (CFA/1) for use as an oral vaccine against enteric infection which has the following steps: (1) growing the E. 5Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 NextLast modified: November 3, 2007