Ex Parte CHEN - Page 7




              Appeal No. 2001-1880                                                                                         
              Application No. 09/273,835                                                                                   
              not normally occur, and not atoms are attached to a nucleotide.”  Brief, pages 7-8.                          
                     We are mindful that it is “improper to add extraneous limitations to a claim, that is                 
              limitations added wholly apart from any need to interpret what the patentee meant by                         
              particular words or phrases in a claim.”  Amgen v. Hoechst Marion Roussel, Inc., 314                         
              F3d 1313, 1393,  65 USPQ2d 1385 (Fed. Cir. 2003).  Courts must take extreme care                             
              when ascertaining the proper scope of the claims, lest they simultaneously import into                       
              the claims limitations that were unintended by the patentee.   See, e.g., Hoganas AB v.                      
              Dresser Indus., Inc., 9 F.3d 948, 950, 28 USPQ2d 1936, 1938 (Fed. Cir. 1993).                                
                     However, it is also well settled that the claims are best understood in light of the                  
              specification of which they are a part.  In the present case, appellant urges that, when                     
              the claims are read in view of the specification, the term “stable isotope-labeled form”                     
              takes on a specific meaning.  In our view, when the claims are read in view of the                           
              specification as elucidated by the prosecution history, they require that all of one type of                 
              atom in a chosen nucleotide unit, for example, all of the carbon atoms, be labeled with                      
              an isotope, consistent with appellant’s interpretation.  Appellant argues (Brief, page 8)                    
              that a “measurement according to the present invention involving less than all of a                          
              chosen element having been replaced by its isotopic form would not yield results that                        
              could be readily analyzed to yield the number of particular nucleotides present in an                        
              oligonucleotide.”   Because the claimed invention would not yield results that could be                      
              readily analyzed if appellant's claim interpretation is not accepted, we find it reasonable                  
              to interpret that the claimed invention as supported by the specification, requires all of                   

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