Ex Parte CHEN - Page 8




              Appeal No. 2001-1880                                                                                         
              Application No. 09/273,835                                                                                   
              the carbon, nitrogen, or hydrogen atoms, be labeled with an isotope.   We also find that                     
              appellant's stable isotope labeled nucleotides, as claimed, are limited to those                             
              nucleotides labeled with 13C, 15N and/or 2H.  Specification, page 6.                                         
                     With this claim interpretation in mind, we review the prior art rejections made of                    
              the application.                                                                                             


              35 U.S.C. § 102                                                                                              
                     Claims 1-4, 6-10 and 13 stand rejected under 35 U.S.C. 102 as anticipated by                          
              Arlinghaus.                                                                                                  
                     A claim is anticipated only if each and every element as set forth in the claim is                    
              found, either expressly or inherently described, in a single prior art reference.”                           
              Verdegaal Bros., Inc. v. Union Oil Co., 814 F.2d 628, 631, 2 USPQ2d 1051, 1053 (Fed.                         
              Cir. 1987).  “It is also an elementary principle of patent law that when, as by a recitation                 
              of ranges or otherwise, a claim covers several compositions, the claim is ‘anticipated’ if                   
              one of them is in the prior art.”  Titanium Metals Corp. of America v. Banner, 778 F.2d                      
              775, 782, 227 USPQ 773, 779 (Fed. Cir. 1985).                                                                
                     The examiner, in the Answer at pages 3-5, has indicated where each of the                             
              claimed steps is disclosed in the Arlinghaus reference.   Arlinghaus (abstract) teaches a                    
              “DNA sequencing, mapping, and diagnostic process which includes the steps of                                 
              labeling nucleotide segments or peptide nucleic acids (PNAs) with one or more atoms                          
              of specific stable or long-lived radioactive isotopes of a selected element that do not                      

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